[Intl_DxMedPhys] Discovery IQ PET/CT Protocol help

[Tyler Bradshaw]

I recall Tim Turkington presented a poster at SNMMI showing that the optimal administered activity for the DIQ was somewhere around 6-8 mCi, regardless of size. Unfortunately, I can’t find the abstract. But you should consider lowering the administered activity and scanning longer (which isn’t convenient, but better than having non-diagnostic quality images). Reach out to Tim for more information.

--
Tyler Bradshaw, PhD
Associate Professor
Director of Clinical Nuclear Medicine Physics
Department of Radiology
University of Wisconsin - Madison
https://urldefense.com/v3/__http://www.lair.radiology.wisc.edu__;!!KGKeukY!x2r1dP47DnQCJOqPlnAaM2Jdlywlu1xCnfH-hAZoqxZYmUgXb9B6-0FXXAKNAGZBG-iUMv6swBHpeqeqTOKcZZtfSAmgAORh96u0P1tJ_w$ 

From: Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list-bounces at lists.osu.edu> On Behalf Of Mike Nimmo via Intl_dxmedphys_wd_osu_list
Sent: Friday, May 15, 2026 10:55 AM
To: Nye, Jonathon <nyej at musc.edu>
Cc: kenharper14 via Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list at lists.osu.edu>
Subject: Re: [Intl_DxMedPhys] Discovery IQ PET/CT Protocol help

Hi Jon, Thanks for your reply. You are exactly right with your assessment. Further feedback from them is that QClear and SharpIR are the scenarios where small lesions have SUV overshoot. So they are hesitant to use those to increase SNR. SUV
Hi Jon,

Thanks for your reply. You are exactly right with your assessment. Further feedback from them is that QClear and SharpIR are the scenarios where small lesions have SUV overshoot. So they are hesitant to use those to increase SNR.

SUV accuracies are within ACR specs for phantom testing. In my testing the SUV values were on the lower range while still passing, which seems kind of typical for GE scanners of this age to me.

On Fri, May 15, 2026 at 10:20 AM Nye, Jonathon via Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list at lists.osu.edu<mailto:intl_dxmedphys_wd_osu_list at lists.osu.edu>> wrote:
Hi Mike, Have you been able to verify the SUV inaccuracies with a phantom? Or is this something that happens only in large patients? In my experience, QClear and SharpIR can cause some overshoot of SUV in small lesions but that was something
Hi Mike,

Have you been able to verify the SUV inaccuracies with a phantom?

Or is this something that happens only in large patients?

In my experience, QClear and SharpIR can cause some overshoot of SUV in small lesions but that was something discovered when the algorithms were first introduced and may be different now.

Jon


Jonathon A. Nye, PhD

Professor, Department of Radiology and Radiological Science

Medical University of South Carolina
99 Jonathan Lucas Drive, MSC 184
Charleston, SC 29425
Phone: (843)-792-4368

________________________________
From: Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list-bounces+nyej=musc.edu at lists.osu.edu<mailto:musc.edu at lists.osu.edu>> on behalf of Mike Nimmo via Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list at lists.osu.edu<mailto:intl_dxmedphys_wd_osu_list at lists.osu.edu>>
Sent: Thursday, May 14, 2026 10:58 AM
To: kenharper14 via Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list at lists.osu.edu<mailto:intl_dxmedphys_wd_osu_list at lists.osu.edu>>
Subject: [Intl_DxMedPhys] Discovery IQ PET/CT Protocol help

Hello, I have a customer who has received delivery of a GE Discovery IQ PET/CT 5 ring system. Their PET radiologist is unhappy with the BGO system's PET image quality for medium to large patients. I was hoping someone out there with a 3
Hello, I have a customer who has received delivery of a GE Discovery IQ PET/CT 5 ring system. Their PET radiologist is unhappy with the BGO system's PET image quality for medium to large patients. I was hoping someone out there with a 3
Hello,

I have a customer who has received delivery of a GE Discovery IQ PET/CT 5 ring system. Their PET radiologist is unhappy with the BGO system's PET image quality for medium to large patients. I was hoping someone out there with a 3 or 5 ring PET/CT system could share their experience and maybe some protocol details with me to pass along.

Particular concerns involve SUV overshoot when detecting small lesions. Also the image quality on medium to large adults is noisy and unsatisfactory. Some things we've been trying to improve image quality are below:

1. Try turning on Q.Clear with Beta values of 200, 250, and 300
2. Increase bed overlap from 19 slices to 35 slices.
3. Changing bedstop acquisition time to 200 seconds or 400 seconds per bed stop for medium to large patients.
4. Using Z-axis standard for small to medium patients and Heavy for larger patients.
5. using Sharp IR

They are still struggling with image quality and SUV accuracy.

Additionally the radiologist appears doubtful whether this scanner will be effective for imaging PSMA or Dotatate studies.

I do not have much experience on this scanner platform so I would appreciate any assistance.

Thanks,

--
Mike Nimmo


--
Mike Nimmo
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