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I recall Tim Turkington presented a poster at SNMMI showing that the optimal administered activity for the DIQ was somewhere around 6-8 mCi, regardless of size. Unfortunately, I can’t find the abstract. But you should consider lowering the administered</div>
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<p class="MsoNormal"><span style="font-family:"Corbel",sans-serif;color:#3A0000">I recall Tim Turkington presented a poster at SNMMI showing that the optimal administered activity for the DIQ was somewhere around 6-8 mCi, regardless of size. Unfortunately,
I can’t find the abstract. But you should consider lowering the administered activity and scanning longer (which isn’t convenient, but better than having non-diagnostic quality images). Reach out to Tim for more information.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Corbel",sans-serif;color:#3A0000"><o:p> </o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-size:8.0pt;font-family:Consolas;color:#999999;border:none windowtext 1.0pt;padding:0in">-- </span><span style="font-size:11.0pt;color:black"><o:p></o:p></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-size:8.0pt;font-family:"Lucida Console";color:#999999">Tyler Bradshaw, PhD</span><span style="font-size:9.5pt;font-family:"Arial",sans-serif;color:#757B80"><br>
</span><span style="font-size:8.0pt;font-family:"Lucida Console";color:#999999">Associate Professor<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:8.0pt;font-family:Consolas;color:#999999">Director of Clinical Nuclear Medicine Physics</span><span style="font-size:9.5pt;font-family:"Arial",sans-serif;color:#757B80"><br>
</span><span style="font-size:8.0pt;font-family:"Lucida Console";color:#999999">Department of Radiology</span><span style="font-size:9.5pt;font-family:"Arial",sans-serif;color:#757B80"><br>
</span><span style="font-size:8.0pt;font-family:"Lucida Console";color:#999999">University of Wisconsin - Madison</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:8.0pt;font-family:Consolas;color:#0B769F"><a href="https://urldefense.com/v3/__http://www.lair.radiology.wisc.edu__;!!KGKeukY!x2r1dP47DnQCJOqPlnAaM2Jdlywlu1xCnfH-hAZoqxZYmUgXb9B6-0FXXAKNAGZBG-iUMv6swBHpeqeqTOKcZZtfSAmgAORh96u0P1tJ_w$"><span style="color:#0B769F">www.lair.radiology.wisc.edu</span></a></span><span style="color:#0B769F"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Corbel",sans-serif;color:#3A0000"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">From:</span></b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"> Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list-bounces@lists.osu.edu>
<b>On Behalf Of </b>Mike Nimmo via Intl_dxmedphys_wd_osu_list<br>
<b>Sent:</b> Friday, May 15, 2026 10:55 AM<br>
<b>To:</b> Nye, Jonathon <nyej@musc.edu><br>
<b>Cc:</b> kenharper14 via Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list@lists.osu.edu><br>
<b>Subject:</b> Re: [Intl_DxMedPhys] Discovery IQ PET/CT Protocol help<o:p></o:p></span></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal" style="mso-line-height-alt:.75pt"><span style="font-size:1.0pt;color:white">Hi Jon, Thanks for your reply. You are exactly right with your assessment. Further feedback from them is that QClear and SharpIR are the scenarios where small lesions
have SUV overshoot. So they are hesitant to use those to increase SNR. SUV<o:p></o:p></span></p>
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<p class="MsoNormal">Hi Jon,<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">Thanks for your reply. You are exactly right with your assessment. Further feedback from them is that QClear and SharpIR are the scenarios where small lesions have SUV overshoot. So they are hesitant to use those to increase SNR.<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">SUV accuracies are within ACR specs for phantom testing. In my testing the SUV values were on the lower range while still passing, which seems kind of typical for GE scanners of this age to me. <o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">On Fri, May 15, 2026 at 10:20<span style="font-family:"Arial",sans-serif"> </span>AM Nye, Jonathon via Intl_dxmedphys_wd_osu_list <<a href="mailto:intl_dxmedphys_wd_osu_list@lists.osu.edu">intl_dxmedphys_wd_osu_list@lists.osu.edu</a>> wrote:<o:p></o:p></p>
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<p class="MsoNormal" style="mso-line-height-alt:.75pt"><span style="font-size:1.0pt;color:white">Hi Mike, Have you been able to verify the SUV inaccuracies with a phantom? Or is this something that happens only in large patients? In my experience, QClear and
SharpIR can cause some overshoot of SUV in small lesions but that was something<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">Hi Mike,<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">Have you been able to verify the SUV inaccuracies with a phantom? <o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">Or is this something that happens only in large patients?<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">In my experience, QClear and SharpIR can cause some overshoot of SUV in small lesions but that was something discovered when the algorithms were first introduced and may be different
now. <o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black">Jon<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;color:black"><o:p> </o:p></span></p>
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<p style="margin:0in;background:white"><span style="font-family:"Calibri",sans-serif;color:black">Jonathon A. Nye, PhD</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black"><o:p></o:p></span></p>
<p style="margin:0in;background:white"><span style="font-family:"Calibri",sans-serif;color:black">Professor, Department of Radiology and Radiological Science</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black"><o:p></o:p></span></p>
<p style="margin:0in;background:white"><span style="font-family:"Calibri",sans-serif;color:black">Medical University of South Carolina</span><span style="font-size:11.0pt;font-family:"Arial",sans-serif;color:#2F5496"><br>
</span><span style="color:black">99 Jonathan Lucas Drive, MSC 184</span><o:p></o:p></p>
<p class="MsoNormal" style="margin-bottom:12.0pt"><span style="color:black">Charleston, SC 29425</span><span style="font-size:11.0pt;font-family:"Arial",sans-serif;color:#2F5496"><br>
</span><span style="font-family:"Calibri",sans-serif;color:black">Phone: (843)-792-4368</span><span style="color:black"><o:p></o:p></span></p>
<div>
<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black">From:</span></b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:black"> Intl_dxmedphys_wd_osu_list <intl_dxmedphys_wd_osu_list-bounces+nyej=<a href="mailto:musc.edu@lists.osu.edu" target="_blank">musc.edu@lists.osu.edu</a>>
on behalf of Mike Nimmo via Intl_dxmedphys_wd_osu_list <<a href="mailto:intl_dxmedphys_wd_osu_list@lists.osu.edu" target="_blank">intl_dxmedphys_wd_osu_list@lists.osu.edu</a>><br>
<b>Sent:</b> Thursday, May 14, 2026 10:58 AM<br>
<b>To:</b> kenharper14 via Intl_dxmedphys_wd_osu_list <<a href="mailto:intl_dxmedphys_wd_osu_list@lists.osu.edu" target="_blank">intl_dxmedphys_wd_osu_list@lists.osu.edu</a>><br>
<b>Subject:</b> [Intl_DxMedPhys] Discovery IQ PET/CT Protocol help</span> <o:p></o:p></p>
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<p class="MsoNormal"> <o:p></o:p></p>
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<p class="MsoNormal" style="mso-line-height-alt:.75pt"><span style="font-size:1.0pt;color:white">Hello, I have a customer who has received delivery of a GE Discovery IQ PET/CT 5 ring system. Their PET radiologist is unhappy with the BGO system's PET image quality
for medium to large patients. I was hoping someone out there with a 3<o:p></o:p></span></p>
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<div>
<p class="MsoNormal" style="mso-line-height-alt:.75pt"><span style="font-size:1.0pt;color:white">Hello, I have a customer who has received delivery of a GE Discovery IQ PET/CT 5 ring system. Their PET radiologist is unhappy with the BGO system's PET image quality
for medium to large patients. I was hoping someone out there with a 3<o:p></o:p></span></p>
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<div>
<p class="MsoNormal">Hello,<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">I have a customer who has received delivery of a GE Discovery IQ PET/CT 5 ring system. Their PET radiologist is unhappy with the BGO system's PET image quality for medium to large patients. I was hoping someone out there with a 3 or 5 ring
PET/CT system could share their experience and maybe some protocol details with me to pass along.<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">Particular concerns involve SUV overshoot when detecting small lesions. Also the image quality on medium to large adults is noisy and unsatisfactory. Some things we've been trying to improve image quality are below:<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">1. Try turning on Q.Clear with Beta values of 200, 250, and 300<o:p></o:p></p>
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<p class="MsoNormal">2. Increase bed overlap from 19 slices to 35 slices.<o:p></o:p></p>
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<p class="MsoNormal">3. Changing bedstop acquisition time to 200 seconds or 400 seconds per bed stop for medium to large patients.<o:p></o:p></p>
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<p class="MsoNormal">4. Using Z-axis standard for small to medium patients and Heavy for larger patients.<o:p></o:p></p>
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<p class="MsoNormal">5. using Sharp IR<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">They are still struggling with image quality and SUV accuracy.<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">Additionally the radiologist appears doubtful whether this scanner will be effective for imaging PSMA or Dotatate studies.<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">I do not have much experience on this scanner platform so I would appreciate any assistance.<o:p></o:p></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal">Thanks,<o:p></o:p></p>
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<p class="MsoNormal"><br>
-- <o:p></o:p></p>
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<p class="MsoNormal">Mike Nimmo<o:p></o:p></p>
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<o:p></o:p></p>
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<span class="gmailsignatureprefix">-- </span><o:p></o:p></p>
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<p class="MsoNormal">Mike Nimmo<o:p></o:p></p>
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