Colloquium speaker, Ahmet Yildiz (UC Berkeley) today at 4pm

[Patterson, Robin L.]

Please join us for the Physics Colloquium today, at 4:00 PM in The Robert Smith Seminar Room. There will be a reception in the Atrium at 3:45PM. Details concerning the talk are as follows:

Speaker:         Ahmet Yildiz (UC Berkeley)
Date:              Tuesday, January 24, 2017
Time:              4:00 PM
Place:            1080 Physics Research Building, The Robert Smith Seminar Room
Title:               The Mechanism of Molecular Motors


Abstract:   The complexity of eukaryotic cells requires intracellular organization, coordination, and locomotion. To overcome these challenges, cells utilize ATP-driven molecular motors, which transport intracellular components unidirectionally along cytoskeletal tracks. Kinesin and cytoplasmic dynein motors facilitate bidirectional transport of a variety of cargos by moving towards the plus- and minus-ends of microtubules, respectively. Detailed mechanistic models exist for kinesin, but the mechanism and regulation of dynein motility are still emerging. We found that dynein walks on a MT through uncoordinated stepping of its two catalytic domains and its mechanism of action differs significantly from the coordinated hand-over-hand stepping of kinesin. Our recent studies present a robust mechanistic model of processivity and force generation that has altered the established views regarding how motors transport intracellular cargos over long distances.


The website for the colloquium is https://physics.osu.edu/physics-colloquium-schedule.


Robin
[The Ohio State University]
Robin Patterson
Program Coordinator
Department of Physics
1040K Physics Research Building, 191 W. Woodruff Avenue, Columbus, OH 43210
(614) 292-8523 Office     (614) 292-7557 Fax
patterson.716 at osu.edu<mailto:patterson.716 at osu.edu> osu.edu<http://osu.edu/>

-------------- next part --------------
A non-text attachment was scrubbed...
Name: winmail.dat
Type: application/ms-tnef
Size: 14402 bytes
Desc: not available
URL: <http://lists.osu.edu/pipermail/physics-staff-df/attachments/20170124/30976689/attachment.bin>