SPECIAL COLLOQUIM - TODAY at 10:00am

Longbrake, Patricia longbrake.6 at osu.edu
Fri Jan 6 09:20:39 EST 2012


Good morning,

Please join us for a Special Colloquium being presented today at 10:00am in the Smith Seminar Room by Comert Kural from Harvard University.  There will be a reception at 9:30a in the Atrium.


TITLE:  "Three-dimensional Analysis of Membrane Trafficking in Living Cells"

ABSTRACT:  Cells require ordered movement of proteins and lipids from one membrane-bound compartment to another. Clathrin-coated vesicles are the most prominent carriers of membrane traffic from cell surface to intracellular organelles (endocytosis), a pathway by which hormones, nutrients, viruses, and their receptors enter cells. They are also important for traffic between organelles. In this presentation, I will discuss (i) technological and analytical advances that I developed to directly visualize clathrin-mediated membrane traffic in three dimensions and in living cells; (ii) data obtained using these advances that defined the mechanism used by cells to counteract membrane tension during clathrin-coated vesicle budding; and (iii) how these advances can be used to study a wide variety of biological processes that occur in living cells and tissues.


Thank you,
Trisch
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