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<p class="MsoNormal">Please join us for a CEM Seminar today featuring <b>Jiao Chen</b><b> from New Mexico Highlands University at 4:00-5:00PM in the Smith Seminar Room in the Physics Research Building</b>. A reception of coffee and cookies will start at 3:30.
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<p class="MsoNormal">“Development and Applications of Gold-Silica Nanohybrids for Bioanalysis”<o:p></o:p></p>
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<p class="MsoNormal">Abstract: An easy, cost-effective, and fast method to synthesize silica nanomaterials has been developed. Desired shapes (hollow/solid spherical, wire-like, rod-like, tadpole-like, etc) can be obtained by simply changing the reaction conditions,
which eliminates the risk of poor reproducibility and brings great potential for a large-scale synthesis. The silica nanomaterials with various shapes were applied in different fields. Take silica nanowire as an example. The length of the synthesized SiNWs
has a typical length up to tens of micrometers and diameter ranging from 60 to 100 nm, which shows their excellent reservoir characteristics and high loading capacity for large molecules. By taking advantages of these properties, we modified the surface of
SiNWs with gold nanoparticles and used them in the photothermal therapy. They showed great cancer cell killing efficiency with a low laser irradiation (0.3 W/cm2). We also applied gold nanoparticles modified silica nanorods (AuNPs-SiNRs) in a dry-reagent strip
biosensor, which presented excellent protein detection ability. The limit of detection was 0.01 ng/mL and had a great linear range from 0.05 ng/mL to 2 ng/mL. The LOD was 50 times lower than that of pure AuNPs-based biosensors.<o:p></o:p></p>
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<p class="MsoNormal">Regards,<o:p></o:p></p>
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<p class="MsoNormal" style="line-height:13.5pt;background:white"><b><span style="font-size:9.0pt;color:#BB0000;background:white">Rachel A. H. Page </span></b><span style="font-size:9.0pt;color:#333333"><br>
Business Administrator<br>
<b>The Ohio State University</b><br>
</span><span style="font-size:9.0pt;color:#BB0000;background:white">Center for Emergent Materials: an NSF MRSEC</span><span style="font-size:9.0pt;color:#333333"> <br>
2004 Physics Research Building | 191 W. Woodruff Ave., Columbus, OH 43210<br>
614-292-2368 Office<br>
<a href="mailto:page.257@osu.edu"><span style="color:blue;background:white">page.257@osu.edu</span></a> <a href="http://cem.osu.edu/"><span style="color:blue;background:white">cem.osu.edu</span></a></span><o:p></o:p></p>
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