<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=us-ascii">
<meta name="Generator" content="Microsoft Word 14 (filtered medium)">
<!--[if !mso]><style>v\:* {behavior:url(#default#VML);}
o\:* {behavior:url(#default#VML);}
w\:* {behavior:url(#default#VML);}
.shape {behavior:url(#default#VML);}
</style><![endif]--><style><!--
/* Font Definitions */
@font-face
{font-family:Helvetica;
panose-1:2 11 6 4 2 2 2 2 2 4;}
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:Tahoma;
panose-1:2 11 6 4 3 5 4 4 2 4;}
@font-face
{font-family:"Bradley Hand ITC";
panose-1:3 7 4 2 5 3 2 3 2 3;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
margin-bottom:.0001pt;
font-size:11.0pt;
font-family:"Calibri","sans-serif";}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:blue;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:purple;
text-decoration:underline;}
p.MsoAcetate, li.MsoAcetate, div.MsoAcetate
{mso-style-priority:99;
mso-style-link:"Balloon Text Char";
margin:0in;
margin-bottom:.0001pt;
font-size:8.0pt;
font-family:"Tahoma","sans-serif";}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri","sans-serif";
color:windowtext;}
span.BalloonTextChar
{mso-style-name:"Balloon Text Char";
mso-style-priority:99;
mso-style-link:"Balloon Text";
font-family:"Tahoma","sans-serif";}
.MsoChpDefault
{mso-style-type:export-only;
font-family:"Calibri","sans-serif";}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-US" link="blue" vlink="purple">
<div class="WordSection1">
<p class="MsoNormal">To all,<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Please come to hear a special colloquium this afternoon by Colin Campbell (Penn State University) at 1:30 PM in the Smith Seminar Room.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Title: The science of complexity: at the intersection of physics and biology<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Abstract: <span lang="EN" style="font-size:10.0pt;font-family:"Arial","sans-serif"">
Many technological, social, and physical systems are characterized by emergent behavior that cannot be predicted from inspection of an isolated component of the system. These so-called complex systems include power grids (with the potential for cascading power
losses), patterns of human interactions (through which many pathogens spread), and the immune system (which functions via many constitutive and comparatively simple biological processes). The methodology of complex systems analysis has been developed in large
part by physicists; I will begin my talk with an introduction to the field and an overview of the methodology. I will then pivot to two case studies with applications to cellular biology. In the first, I will discuss topological measures that capture the regulatory
behavior of complex biological networks; in the second, I will discuss a novel computational methodology for identifying potential interventions into regulatory biological networks that have been damaged, e.g. through a genetic mutation that leads to cancer.
I will close with an overview of the state of the field and avenues for future research.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN" style="font-size:10.0pt;font-family:"Arial","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN" style="font-size:10.0pt;font-family:"Arial","sans-serif"">Please come and support our regional campus search –<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN" style="font-size:10.0pt;font-family:"Arial","sans-serif""><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN" style="font-size:10.0pt;font-family:"Arial","sans-serif"">REFRESHMENTS WILL BE SERVED AT 1:15PM</span><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><span style="font-family:"Bradley Hand ITC"">Shelley<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:13.5pt;background:white">
<span style="font-size:9.0pt;font-family:"Helvetica","sans-serif";color:#333333"><img width="280" height="56" id="Picture_x0020_1" src="cid:image001.png@01CF2C89.06B01B20" alt="The Ohio State University"><br>
</span><b><span style="font-size:9.0pt;font-family:"Helvetica","sans-serif";color:#BB0000;background:white">Shelley Palmer</span></b><span style="font-size:9.0pt;font-family:"Helvetica","sans-serif";color:#333333"><br>
Administrative Associate to the Chair<br>
</span><span style="font-size:9.0pt;font-family:"Helvetica","sans-serif";color:#BB0000;background:white">Department of Physics</span><span style="font-size:9.0pt;font-family:"Helvetica","sans-serif";color:#333333">
<br>
1040P Physics Research Building, 191 W. Woodruff Avenue, Columbus, OH 43210<br>
(614) 292-2653 Office<br>
<a href="mailto:palmer.14@osu.edu"><span style="background:white">palmer.14@osu.edu</span></a>
<a href="http://osu.edu"><span style="background:white">osu.edu</span></a> <o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>